… of humoral and cell-mediated immunity induced by mRNA vaccines expressing influenza hemagglutinin stem and nucleoprotein in mice and nonhuman primates

JA Flynn, T Weber, PJ Cejas, KS Cox, S Touch… - Vaccine, 2022 - Elsevier
… To evaluate the potential of the HA stem vaccine to elicit Fc-mediated effector function, we
tested the vaccine sera in an in vitro surrogate antibody-dependent cell-mediated cytotoxicity (…

NS1 DNA vaccination protects against Zika infection through T cellmediated immunity in immunocompetent mice

B Grubor-Bauk, DK Wijesundara, M Masavuli… - Science …, 2019 - science.org
… mediate antibody-dependent cell-mediated cytotoxicity (… protection in an intracranial
model of ZIKV infection (31, 32). … role of NS1-specific cell-mediated immune (CMI) responses …

Murine Cytomegalovirus Enters Diverse Cell Types by the Novel Receptor Neuropilin-1

RK Lane - 2020 - search.proquest.com
… Since herpesviruses are highly species-specific, the study of CMV infection in vivo …
models of CMV infection: murine cytomegalovirus (MCMV) and guinea pig cytomegalovirus (GPCMV). …

Pre-existing immunity to cytomegalovirus in macaques influences human CMV vaccine responses in preclinical models

H Webster, S Valencia, A Kumar, C Chan, M Dennis… - Vaccine, 2021 - Elsevier
… Antibodies directed at gB can be neutralizing or non-… cell-mediated effector functions,
like antibody-dependent cell phagocytosis (ADCP) or antibody dependent cell cytotoxicity (ADCC). …

MicroRNA-155 and antiviral immune responses

A Jafarzadeh, A Naseri, L Shojaie, M Nemati… - International …, 2021 - Elsevier
… including both humoral/cell-mediated immunity and innate … kill infected cells directly and
also by antibody-dependent … cell activity during murine cytomegalovirus (MCMV) infection. Both …

Roles of natural killer cell receptors and adaptors in anti-tumor and anti-virus immunity

R Li - 2022 - escholarship.mcgill.ca
… NK cell-mediated cytotoxicity can also lyse target cells into … responses against mouse
cytomegalovirus (MCMV) infection (51). … antibody-dependent cellular cytotoxicity (ADCC) towards …

[PDF][PDF] A vaccine inducing solely cytotoxic T lymphocytes fully prevents Zika virus infection and fetal damage

F Gambino, W Tai, D Voronin, Y Zhang, X Zhang, J Shi… - Cell reports, 2021 - cell.com
… As vaccine-induced non-neutralizing antibodies may cause antibody-dependent enhancement
of Zika virus (ZIKV) infection, we test a vaccine that induces only specific cytotoxic T …

Human cytomegalovirus glycoprotein B nucleoside-modified mRNA vaccine elicits antibody responses with greater durability and breadth than MF59-adjuvanted gB …

CS Nelson, JA Jenks, N Pardi, M Goodwin… - Journal of …, 2020 - Am Soc Microbiol
… to have good agreement with antibody-dependent cellular cytotoxicity activity for rabbit
serum (17). MRC-5 cells were infected with the BadrUL131-Y4 strain at an MOI of 1.0 for 48 h …

A multi-targeting, nucleoside-modified mRNA influenza virus vaccine provides broad protection in mice

AW Freyn, JR da Silva, VC Rosado, CM Bliss, M Pine… - Molecular Therapy, 2020 - cell.com
Influenza viruses are respiratory pathogens of public health concern worldwide with up to
650,000 deaths occurring each year. Seasonal influenza virus vaccines are employed to …

The Role of Natural Killer Cells in the Tumor Immune Microenvironment of EBV-Associated Nasopharyngeal Carcinoma

S Li, W Dai, NW Kam, J Zhang, VHF Lee, X Ren… - Cancers, 2024 - mdpi.com
anti-virus abilities. The cytokine and cellular interaction features of NK cells are distinct from
those of CD8 + cytotoxic … and inducing antibody-dependent cell-mediated cytotoxicity (ADCC)…